PharmBioTec Research & Development GmbH offers a range of high-quality services at various stages of the development process of new active ingredients and formulations. From the synthesis of active ingredients and excipients, through testing for efficacy and safety and development of the formulation to final quality control, PharmBioTec is a GMP-certified company and your partner for all your questions.
We offer high-quality analytical services and quality control of active ingredients, excipients and finished drugs under GMP
conditions. The instrumentation includes HPLC-UV, HPLC-DAD, HPLC-MS, HPLC-hrMS, HPLC-MS/MS, UV, IR, CE-SDS, CE-UV, CE-DAD, CE-MS, ultra-high-resolution mass spectrometry as well as moisture
analysis by Karl-Fischer (volumetric, coulometric, oven technology). In addition, our service includes rheological characterization for formulation development of semi-solid and solid
formulations (oscillating and rotating).
In the area of production, we offer services related to the synthesis of active ingredients and excipients in small batches (from a few g to around 10 kg) under controlled conditions. In combination with our certified analytics, you receive high-quality substances that are synthesized according to your specifications. In addition, we offer services in the field of design and synthesis of substance libraries for hit-to-lead and lead optimization.
Formulation development and in vitro efficacy & safety
The Drug Delivery department specializes in the development of new formulations (e.g. inhalants, creams, innovative nanocarriers). In
order to avoid animal experiments, the formulations are tested on specially designed in vitro or ex vivo models. For example, on cell culture models of the lung or intestine, on skin or teeth
depending on the individual problem.